Organic-4

1 .How to convert:
(a) CH≡CH into CH3COOH (b) HCHO Glycine (c) HCHO Ter Butyl alcohol (d) Nitrobenzene into Benzene (e) Methylamine into ethylamine (f) Propanoic acid into Acetic acid (g) Benzene into cyanobenzene (h) Toluene into m-nitro benzoic acid (i) Benzene into Benzaldehyde (2 steps) (j) Propanoic acid to 3 Pent none
2.Complete the following reaction
Ethylisocynide undergoes acidic hydrolysis Ans N-ethylformamide
3.write down example of
1. Perkins reaction 2.benzoin condensation 3.Knowengeal reaction
4. Why acylation occurs before nitration of aniline?
5.Explain (a) The Zwitter ion.(b)Acidic nature of Alpha hydrogen of nitro & carbonyl compounds?
(c)Explain basic nature of (C2H5)2NH > (C2H5)3N > C2H5NH2
(d)Why aniline is weaker base than ammonia? (e) There are two NH2 group in semi carbazide.However only one is involved in formation of semi carbazone
6. Write the difference between: (a) enantiomers & distereomer (b) Chirality’s & chiral (c) Racemic modification & meso compound
7. Write IUPAC name of the following:
Aspirin ,Salol ,orthoformic ester
8.How to distinguish between :
(a)Phenol & Benzyl alcohol (b) Chlorobenzene & Benzyl chloride (c) CH3-CH2-OH & CH3-CH=O
(d) HCHO & HCOOH (e) (f) RNO2 & R-O-N=O
(g) 10 20 30 alcohol (h) HCHO & CH3CHO (i) 10 20 30 amine (J)HCOOH& CH3COOH
9.How to convert :
1. (a) Benzene to Benzoic acid through nitration (b)benzene to Aspirin (c)Chlorobenzene to DDT
(d) HCH=O to ter butyl alcohol (e) Prop none to CHI3 (f) CHCl3 to diethyl carbonate (g) Ethanal to Crotanaldehyde (h) Toluene to m-nitro benzoic acid (i) Aniline to nitro aniline
(j) CH2=O to 1-Butanol
10.. What happens when:
1. 10 amine reacts with CHCl3 & KOH (alc) (b) HCHO & C6H5CHO reacts with conc. KOH
(c) Aniline react with CHCl3 (d) Toluene reacts with Cl2 in the presence of aq. NaOH
(e) CH2=O kept at room temp. (f) Aniline react with conc H2SO4 reacts with conc. HNO3 & H2SO4
(g) FeCl3 reacts with aq. Solution of 10amine
(h) Glycerol reacts with conc. HNO3 (i)Anisole reacts with cold & dil. HI
(j) Ter. Butyl alcohol passed over heated Cu (k) CH2=CH2 reacts with PdCl2 & H2O
11.Explain : (a) Reductive amination of aldehyde & ketone (b) Why phenol is easily nitrated in comparison to toluene? (c) Why para nitro phenol is more acidic than ortho nitro phenol? (d) Why anisole does not give iodo benzene when reacted with conc.hot HI?
12. Give reasons for:
(a)Why AgCl is soluble in RNH2 (b) Why trichloroacetic acid is more acidic than CH3COOH
(c) Why CH3-CH=CH2 with HBr in the presence of peroxide gives 1 bromo Propane (d) Why Benzyl amine is more basic than aniline (e) Why aryl halide is less than reactive than alkyl halide
13. Write short note on:
(a)Rosemund Reduction (b) Protonation (c) Transesterification (d) Williamson Synthesis
(e) Oxo reaction (f) Schotten Baumann reaction
14. Write all the isomers of C4H10O & C7H9N
15. Explain (a) The Zwitter ion. (b) Acidic nature of Alpha hydrogen of nitro & carbonyl compounds? (c)Explain basic nature of (C2H5)2NH > (C2H5)3N > C2H5NH2
16.(a)Why aniline is weaker base than ammonia? (b) There are two NH2 group in semi carbazide.However only one is involved in formation of semi carbazone.
17.How to differentiate : a. Nitro & Nitrite b. Aniline & Phenol c. Formaldehyde & formic acid d. Methyl acetate & Ethyl acetate e.Primary amine, secondary amine & tertiary amine f. Acetaldehyde & Prop anal
18.What happens when: (a) Aniline reacts with alcoholic chloroform (b) Alkyl Cyanide undergoes basic hydrolysis (c) Nitrobenzene is reduced in neutral medium (d) Acetaldehyde reacts with dilute NaOH.
19.Write short note on: (a) Gabriel Pthalamide Synthesis (b) Hoffmann Bromamide Reaction (c) Carbyl Amine Test (d) Hoffmann Ammonolysis (e) Sand Mayer Reaction (f)Diazotization reaction (g) Schotten Baumann Reaction (h) Cannizaro Reaction
20.(a) How to convert (a) nitrobenzene into aniline (b) Nitro methane to 1-Nitro Prop-1-ene (c) Ethanol to 3-hydroxy but anal (d) Prop anal to but anal (e) Ethyl magnesium bromide to 2-methyl propanol-2
21.Write the structure of (a) Sulphanilic acid (b) Picric acid (c) 1-Methoxy 3-nitro benzene (d) Crotan Aldehyde (e) Quaternary Methyl ethyl propyl butyl ammonium chloride